For undergraduate engineering admission the paper is based on the class 12 syllabus in physics, chemistry and mathematics, with objective questions and a marking scheme published in the admission notification. Papers for management, computer application, pharmacy, science and other streams draw on the relevant qualifying-level subjects together with general aptitude, reasoning and English where appropriate, while postgraduate papers test the core content of the corresponding bachelor's degree. The resulting score is used only to build a programme-wise merit list for admission to Quantum University, after which candidates confirm their seat through the university's counselling process. Some courses may include an interview or additional assessment where notified. The number of questions, the duration, the mode of the test, the test centres or online arrangement, and the application and result timetable are announced by the university for each admission session.

Applicants to undergraduate engineering programmes must have passed class 12 or an equivalent examination from a recognised board with physics and mathematics together with chemistry or another prescribed subject such as biology, biotechnology or a technical vocational subject. Applicants to other undergraduate courses must have class 12 with the subject combination specified for that course. Postgraduate applicants must hold a relevant bachelor's degree from a recognised university, with management programmes generally open to any discipline. Candidates awaiting results may apply provisionally. The minimum marks required, any age condition and the alternative entrance scores accepted in place of the university test are stated in the official admission notification published by Quantum University.